Pre-cut lamellae improve graft quality
DMEK is a highly specialised, minimally invasive surgical method with very good results in the treatment of endothelial corneal diseases. However, the required lamella preparation also stresses this sensitive tissue. If the preparation is done directly in the operating theatre immediately before the transplantation, the period of stressful surgery is prolonged. Cells may die. However, the longer the graft can rest after preparation, the more cells survive and can provide clear vision in the end.
Studies by an interdisciplinary research team in the DGFG network show that the pre-cutting of corneal lamellae in the tissue bank does not have a negative effect on graft quality. On the contrary: pre-cut lamellae contribute to graft improvement. The endothelial cells located on the descemet lamella can recover after a rest period between preparation and transplantation.