Amniotic membrane for wound healing

The amniotic membrane is the inner egg membrane of the maternal placenta that faces the fetus. A placenta donation is a living tissue donation. Prerequisites are the consent of the mother and a planned Caesarean section birth. Due to its excellent wound healing properties, the amniotic membrane can be used in various areas of medicine. Patients benefit from a gentle and fast healing method. The amniotic membrane is used, for example, in ophthalmology for the treatment of eye injuries or in oral and maxillofacial surgery, where it can be placed on larger wounds. The amniotic membrane is currently being processed in the cornea and tissue bank Schwerin, a joint tissue bank of the Helios Kliniken Schwerin and the DGFG.

Fields of application

  • Ophthalmological and orbital procedures
  • Temporary skin replacement for thermal injuries and wound healing disorders
  • Gynaecological surgery: uterus and vagina
  • Oral and maxillofacial surgery: oral and maxillofacial procedures

Here you can see an amniotic membrane be dissected from the placenta.

Amnion transplants are available in four different sizes

Transplant sizes

Amniotic transplants can be ordered from the DGFG in the following four sizes:

  • 20 x 20 mm
  • 35 x 35 mm
  • 50 x 50 mm
  • 70 x 70 mm

Delivery within Germany

Delivery on dry ice usually takes place on the next working day. The transplant centre has to sign an acceptance commitment. When ordering amniotic transplants (Monday to Friday until 1.30 p.m.) there is usually no waiting time. The DGFG charges an expense reimbursement for the provision of the transplants and a fixed transport fee for the delivery. If several amniotic transplants are ordered, the fee for transport will only be charged once. On-site storage is possible. A separate permit is not required. Storage in a freezer of at least -60°C is required. Traceability must also be ensured during storage. It is not necessary to forward the patient data to the DGFG.

International delivery

A transfer of amniotic transplants to international locations is possible if the import is approved and all necessary documents are available. The tissue allocation office and the quality management of the DGFG will help with the clarification and implementation.
The delivery time for orders outside Germany is dependent on the distance and country-specific requirements. The DGFG makes every effort to keep waiting times as short as possible. For increased flexibility, it is possible to store several amniotic transplants on site in a suitable freezer (< -60°C). The DGFG charges an expense allowance for the provision of the transplants and the transport costs for the delivery.

Package leaflet

The “human amniotic membrane, cryopreserved, Schwerin” is delivered deep-frozen in a sterile container. It must be stored at temperatures below -60°C (freezer or on dry ice) until 30min prior to the surgery. The amniotic membrane has to be used within six hours after thawing and must not be refrozen once thawing has begun. The maximum storage time (with continuous temperature monitoring of the freezer) is 12 months from the date of manufacture and only if the amniotic membrane has been transferred to a suitable -60°C freezer in the sterile container immediately after receipt. The medicinal product is intended for single use only. The contents of a package are intended exclusively for use on a single patient.